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Used to refer to a female fictional character that the user experiences attraction to.

The term originated from the manga Azumanga Daioh, where character Mr Kimura uses the term to refer to his actual wife. (Yes, the original definition is literally just "wife" in Engrish.)
Guy 1: "(insert character here) is my waifu"
Guy 2: "(insert tangent about Azumanga Daioh)
waifu by CapTouhou June 13, 2022
Related Words
Best girl in anime who puts all other female characters to shame. If she were real you would do whatever it took to make her your bride

See: "Froppy" from My Hero Academia
"I want to make her my Waifu! If only she were real..."
Waifu by fatjohnson2023 March 9, 2023
A waifu is a fictional character that whom a person find as their romantic partner.
Weeb: "Ruby Hoshino is my waifu!!"

"KILL YOURSELF"
Waifu by reiomo July 21, 2023
Speedwagon

Speedwagon from JoJo’s Bizarre Adventure is the true definition of a waifu.

Speedwagon has all of the attributes of a true waifu
The real waifu is speedwagon
Agreed
Waifu by BuonGioGio July 26, 2023
Waifu, a term used for your greatest love, Cocaine.
Where da waifu?
"Where is the cocaine"
Waifu by SumLink December 9, 2023