Ur sisters a mister

Even worse than ur mom gay, ur dad lesbian and ur granny tranny! Makes Jupiter explode!
Pete: Ur granny tranny
Alex: Ur sisters a mister
Jupiter *explodes*
by JrgnVS March 14, 2018
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Ur sister a mister

The worse possible insult above "ur mom gay" "ur dad lesbian" "ur granny a tranny" and "ur granpap a trap"
James: lol ur mom gay
Holden: ur dad lesbian
James: ur granny a tranny
Holden: ur granpap a trap
James: well ur sister a mister
Holden: *shrivels up and dies*
by Stakeynya May 13, 2018
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ur sister

Mark: ur mom
Jack: ur sister
Mark: kys
by zandingo January 27, 2020
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ur sister mister

Ur sister mister is the next level of ur granny tranny. It is stronger than ur mom gay, ur dad lesbian and ur granny tranny combined. Nobody who ever heard this sentence is alive.
John: Hey Jeff ur mom gay
Jeff: No u
John: Ur dad lesbian
Jeff: Ur granny tranny
John: Ur sister mister
Jeff: *jeff and his whole family instantly die and go to the deepest layer of hell*
by TheRealMemeGod March 14, 2018
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ur sister a mister

The absolute killer of 'ur mom gay' 'ur dad lesbian' 'ur granny a tranny' and 'your grandpap a trap'.
Henry: Don't make do it.
Joe: Do it pussy.
Henry: Ur grandpap a trap.
Joe: Bitch please.
Joe: Ur sister a mister.
*Henry's body turns into dust*
by LoCaboose March 13, 2018
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ur sister a mister

If the "Your Granny and TRANNY!" get pulled out you must say "YOUR SISTER A MISTER!!" and this rude human will die of brain cancer.
Tim"You are a cunt"
Me"No you"
Tim"Ur dad has big gay"
Me"No u"
Tim"Your granny tranny"
Me"Your sister a mister"
Tim *DIES*
by Gayuun May 10, 2018
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