Carlos, spurred by his desire to quickly climb the ladder, decided to step it up a notch and take out a rival drug lord by giving him a Panama Caboose.
by cheesewheezy June 4, 2009

used to refer to a person with a loose anus. Usually happens when said person has participated in copious amounts of anal sex.
by Anal Jim April 25, 2011

"Dude, that mexican food went right through me! When I got home I headed straight for the deuce caboose and dropped one, wait I mean two!
by Dustin Crew November 23, 2007

Any female that frequents the scumfuck bar The Loose Caboose (The Loose Asshole) in Lafayette, Louisiana.
Typically a college-aged female, but not necesarily college student, who listens to nu metal, has tribal tattoo(s), still wears the same Jncos bought from Gadzooks in 97', and has a myriad of issues that require her to take depakote or some other crazy person medication.
by POND SCUM October 1, 2004

While walking down the street, Allison noticed a caboose on the loose named Sam who was wearing shoes on her hands
by Allinella June 17, 2010

girl one: " I very much enjoyed your caboose mousse.
girl two: "did it come out too fast? Hurry, puke in my mouth."
girl two: "did it come out too fast? Hurry, puke in my mouth."
by aboozed February 20, 2011

by Peanut_Butter September 23, 2012
