Tweak

–verb

1. To get very angry or randomly mad
2. To freak out
3. To yell

May also be seen as:
Tweak'ing
Tweak'er
Tweaking Balls

"Yo she's tweaking balls"
"What's with all the tweaking?"
"He's a tweaker!"

by Tehbs. July 7, 2009

Tweak

(v) to tweak: a high resulting from methampetamines

He's the biggest druggie, he tweaks everyday.

by Cacoo June 26, 2003

Tweak

1. To adjust accordingly
2. To freak out

1. His guitar sounds like shit 'cause he's gotta tweak his amp.
2. When she heard me play my guitar she tweaked.

by Buzz Cola October 23, 2003

Tweak

Really jumpy, talks with his hands, basically the baddest mofo on a campus near you.

Look at tweak walkin outta math class.

by snaggatoof February 6, 2010

Tweaking

Obsessive repetitive behavior

Look at him hes tweaking out!

by Slim kitty February 7, 2017

tweak

1. to adjust slightly

2. to adjust a computer program slightly

They tweaked the game to fix a glitch.

by Light Joker September 2, 2007

tweak

v- to tweak
to be extra twitchy, secretive, giggly while under the influence of weed, pot, marijuana
to have the tell-tale signs of being high (squinty eyes, blood-shot eyes)

"Yo after taking those five rips off the bong, I was totally tweaking out. I was pulling my hoodie all the way down, I put sunglasses on, and my eyes were BARELY open"

by bnell9002 December 28, 2005