Duff

The brand of beer that Homer drinks in the Simpsons.

Duffman approves this definition

by kunemvu February 23, 2020

Duff

The ugly friend you bring out with you.

Ian is not a Duff

by QuinnIsAJag January 19, 2020

Duff

Dumb, Ugly, Fat, friend

Oh my gosh she is such a duff..

by gamerpeeps500 August 23, 2021

dorcus duff

the local hoodrat or prostitute

guy 1- "did you see that chick on sleeping on the road"
guy 2- "yea must be a dorcus duff"

by jayquan24 September 13, 2020

duff

Dump
Ugly

Fat
Friend

That girl is the other's duff.

by Masker August 10, 2017

Duff Buck

A currency used by 8th grade students on the Hawks side of Chichester Middle School that Mr. Bryan Duffy created during his time teaching for his students to earn and purchase valuables such as buying extra credit points on the final exam, buying a homework pass or a mechanical pencil.

Student: I would like to use a homework pass
Mr. Duffy: *Takes the Duff Bucks and marks as complete*

by VinnySarge June 10, 2025

Duff

Designated Ugly Fat Friend

Usually the unattractive one in a group of friends. Basically the outcast

All my friends are beautiful, this means I'm the duff😭😔💔

by Starbeauty November 28, 2020