I.S 383 

Where you have treeshes sucking dick in the stairways and teachers caring more about your hoodies then your education!

Dam you been to I.S 383? Hurd tri*** was sucking dick

I.S 383 by Treesh-Ana November 14, 2019

I.S.M.P.F.L.

I Shit My Pants From Laughing

dude, ashley queefed in the middle of class! I.S.M.P.F.L.

I.S.M.P.F.L. by schlipdopp yummm February 22, 2010

I.S.O.M 

I
Suck
Off
Men
I.s.o.m is a phrase use withing the gay community to let others know that they would like to give them sloppy toppy without being too forthcoming.

Man 1- hey you know what's my favorite thing?
Man 2- what's that?

Man 1- I.S.O.M *wink wink*

*Man 2 and the surrounding men followed Man 1 into the back and fill him up to the point where he has to get his stomach pumped*

I.S.O.M by The last melon February 11, 2019

I's out 

1. A way to announce your departure. Short for I is out; it involves being ignant on purpose because gramatically it should be "I am out".

2. Can be used at the end of a txt conversation.

1. Alright guys, it's getting late, I's out.

2. Rose: I'll talk to you later, I's out.
Niesz: Peace.

I's out by Niesz November 6, 2006

I.S.U.B. 

An abbreviation for the phrase "I'll slap you (u) bitch!"
Commonly used by angry nerds asleep in bed at night talking to their imaginary girlfriends. It can also be used in the pase tense such as "I slapped ur (your) bitch!"

Examples of I.S.U.B.
"ISUB if you don't pull harder!"
"Last night ISUB"
"Last night, I slapped your bitch!"
"I'd slap you bitch!"
"I'll slap you bitch!"

I.S.U.B. by Urban Dic-tionary Stalker October 26, 2009

I.S.O.Y. 

Incognito Schemers of Yorkville

Don’t mess with I.S.O.Y.

I.S.O.Y. by cityrunner August 16, 2019

I.S.T.C.F.F.U 

I’m starting to catch feelings for you...

Yo babes you good eh... I.S.T.C.F.F.U

I.S.T.C.F.F.U by Uhm just words December 2, 2020