It is the syndrome most girls get (but some boys too) after they "make love" for their first time. And it doesn't matter if the dude/girl they did it with is the biggest loser/idiot/asshole whatever, they will give them every chance in the world no matter what other people say.
Girl: hey, I think I'm gonna give my x another chance.
Boy: Damn girl are you crazy?!? Listen I gotta know somethin. Did you give it up to him?
Girl: ya
Boy: Aahh damn girl thats why you keep giving him chances, you got that First Fuck Syndrome!
Boy: Damn girl are you crazy?!? Listen I gotta know somethin. Did you give it up to him?
Girl: ya
Boy: Aahh damn girl thats why you keep giving him chances, you got that First Fuck Syndrome!
by Ferd to the Word April 30, 2009

a condition that can occur when a person who is bent over, or in any awkward position, sneezes, coughs, hiccups, and belches all at the same time, causing the heart to flip over inside the chest cavity.
The condition is extremely painful, but if the victim survives the initial shock, they can recover as the elasticity of the major arteries is usually sufficient to slowly pull the heart back into proper position.
Do NOT move the victim.
The condition is extremely painful, but if the victim survives the initial shock, they can recover as the elasticity of the major arteries is usually sufficient to slowly pull the heart back into proper position.
Do NOT move the victim.
by Figleaf23 November 26, 2009

Emotional condition akin to anger that a rational person feels when surrounded by retarded people. It is also akin to having your head hammered by Kraut.
Today 85% of Americans suffer Bush Derangement Syndrome due to prolonged exposure to Bush administration.
by Krauthammer February 25, 2009

A serious affliction that seems to affect celebrities only. When a formerly paparazzi-friendly celebrity stops talking to the cameras after entering a serious relationship. Named after John Mayer, who was glacial towards paparazzi during his relationship with Jennifer Aniston. Originally coined by Harvey Levin of TMZ.
After British lothario Russell Brand said he was "in love" with Katy Perry, he stopped talking to paparazzi. She gave him John Mayer Syndrome.
by geeksmakethebestlovers October 28, 2009

(Noun) A contagious disease spread by over zealous males, or in some cases females, being standoffish toolbags. Although not given enough credit and awareness by Congress and the Environmental Protection Agency (EPA), there are many ITS (Insufferable Toolbag Syndrome) pandemics spreading throughout several nations, including the United States, Canada, and France. The only cure to this terrible disease is a good, humiliating slap to the face, or roundhouse kick for those in the footsteps of Chuck Norris, to humble those with the disease. ITS tends to come back and effect people multiple times, so 3 additional slaps-to-the-faces are recommending to suspend ITS for a longer period of time.
John:"Look at Andy, just sitting there playing his guitar while all the girls gaze at him."
Jane:"I think he might have Insufferable Toolbag Syndrome.... You know what to do John. It's for the best."
John: slaps Andy across the face repeatedly until all the girls run away.
John:"I can't stand it when he talks, he's such a tool!"
Jane:"Then go slap him!"
John:"No... I'll roundhouse kick him to the face. It's the most effective way to cure Insufferable Toolbag Syndrome."
Jane:"I think he might have Insufferable Toolbag Syndrome.... You know what to do John. It's for the best."
John: slaps Andy across the face repeatedly until all the girls run away.
John:"I can't stand it when he talks, he's such a tool!"
Jane:"Then go slap him!"
John:"No... I'll roundhouse kick him to the face. It's the most effective way to cure Insufferable Toolbag Syndrome."
by ncmo April 26, 2010

Cancerous syndrome that gets spread by cringey 12 yr olds. The simptoms are: dabbing, saying "lit" over and over again, singing dumb songs, and buying pieces of "merch"
by Jordanme November 1, 2017

A state when a girl has a strong partially unhealthy, attraction to a boy she like and thinks about him constantly. The symptoms often include, Long hours creeping photos on face book, becoming excellently nervous around said boy, forgetting her name when introducing her self, and vomiting.
Can also appear in gay boys who don't know how to date.
Can also appear in gay boys who don't know how to date.
Girl: look there is the boy I like, I'm going to go over and talk to him.
Girl's friend: I don't know, you seem to have a severe case of Teen Girl Syndrome, is that wise?
Girl: No, I'll be fine, really.
Girl walks over to boy
Girl Hi, I'm... *Vomits on boys shoes*
Girl returns to her friend in shame
Girl's friend: You threw up on his shoes again didn't you?
Girl: I think he likes me.
Girl's friend: I'm sure.
Girl's friend: I don't know, you seem to have a severe case of Teen Girl Syndrome, is that wise?
Girl: No, I'll be fine, really.
Girl walks over to boy
Girl Hi, I'm... *Vomits on boys shoes*
Girl returns to her friend in shame
Girl's friend: You threw up on his shoes again didn't you?
Girl: I think he likes me.
Girl's friend: I'm sure.
by Dr.P.Schot November 15, 2011
