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I wouldn't piss up your ass if your guts were on fire. 

The ultimate FUCK YOU.
I would rather watch you die from internal hellfire, rather than extinguish your flaming innards with my urine.
Suzie: Hey man you are a fucking dick, why do you treat everyone like shit?

Balls Hampton: Fuck you bitch! I wouldn't piss up your ass if your guts were on fire.

Suzie: Weeps uncontrollably

more fun than a clown on fire 

to be exceedingly entertaining, much like a clown on fire
Listening to Bush try to talk about foreign affairs is more fun than a clown on fire

the roof is on fire 

1.This party is jumpin!

2. Some one started a fire on the roof.
the roof is on fire by Gretchen March 26, 2003

hair on fire 

A state of being super busy or overwhelmed. When your hair is on fire, you are consumed with reacting to an emergency and have not time to deal with ankle biters.
It was one of those hair on fire moments where everyone and their brother was requiesting things from me at the same time.

Do you need help? it looks like your hair is on fire.

I am sorry I didn't call you back; my hair was on fire at work.
hair on fire by RCU December 4, 2014

get along like a house on fire 

To have a great relationship with someone quickly.
" I was worried when my boyfriend and father met for the first time. However, they got along like a house on fire because they both like watching football and playing poker."

A: Do you like your new roommate?
B: Yeah! We get along like a house on fire! We both like the same things and we are both clean people!

high on fire 

this one dude: have you heard of high on fire man?

this other dude: ya, i have