I.S.S.

Imperial Star Ship

Prefix used by the Terran Empire; from the original Star Trek episode "Mirror, Mirror";

Computer: "...succeeded to command of I.S.S. Enterprise through assasination of...."

by WitnessX June 20, 2006

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I.S. 59

One of The most ghetto queens schools. Would Not recommend as a middle school. Mad treeshes, fights almost everyday, bum ass teachers, weave always in the hallway when there’s a girl fight, mad dykes, but we always find a way to get lit.

Bro what school you going to? I might go to I.S. 59.

by 59 reader May 17, 2020

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I.S

Immortal Sinners: Can sin over and over but nothing kills or stop, savage to the most.

How are you so strong? Im an immortal sinner hoe! (I.S)

by SavageeeeeDeathSinner November 30, 2017

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I.S

The shortened street term for Interview session. Usually people would use this when they’re trying to rush the conversation or just let people know where they’re making their way too. It’s often used casually though.

I saw you with a guy last week what was that all about?

I was holding an I.S with him to get to know him.

by Daddy yo slay (; March 10, 2020

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I.S.75

All the faggots go there and all the girls are treeshes

Yo you know any girls I could date in I.S.75?
Yea bro any girl you put your mind to bc they’ll say yes even if your the most ugly person known to man.
THANKS BRO!

by Barney the dinosaur August 21, 2019

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