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Dopaminergic Antagonist 

The ultimate kill joy. Someone who makes others so miserable, he/she suppress the effects of dopamine on mood.
Your boss is such a dopaminergic antagonist that every time you have a meeting with him, you're depressed for the rest of the month.
Related Words

Summer anting 

When someone goes on about some bullshit no one cares about.
Well, actually, xxx is xxx because xxx, isn't that interesting? See.. summer anting.
Summer anting by mjx.aep October 19, 2023

antagonist 

the character in a good vs. evil plot that opposes the good/hero.
everyone seems to root for the hero's in stories...but i like to root for the antagonist
antagonist by Altgirl August 25, 2006
a small city in northern wisconsin that nobody outside of antigonians knows about. mainly consists of drugs and fast food restaurants. boring. small. unknown to most. antigo
Dude: So where are you from?
Chick: antigo!!
Dude: where?
antigo by MaryJane69 December 13, 2010

antagonistic 

being antagonistic is opposing progress or being negative and possibly being hostile.
Stop being so antagonistic. I know it wasn't the plan but, it's not too big a deal if you come earlier and help out.
antagonistic by O-J September 5, 2006

Antigoni 

"Anti" meaning against in GREEK and for whoever wrote before me "Goni" comes from the GREEK word "Gonies" which means Parental Eye. Antigoni is a REBEL!!!
Princess Antigoni of Ancient Greece rebelled against her uncle who had caused a war between her two brothers (Futur Kings of the Country) making both of them die. The Brother who had honored the Uncle years before had a proper burial were as the other was left to rot. Antigoni, defying her uncles orders went later that night and buried her brother. For that she was condemned to death.
Antigoni by Antigoni487 June 9, 2010