Late Night Brain Syndrome 

The condition of your brain in which late at night you think of things that make you sad, such as memories with an Ex or just fun times that you wish you could repeat and relive forever.
It also includes thinking of someone you like, but knowing that they don't like you back, or you're too afraid to find out if they do or not, therefore, you will never get to be with them.

Jay: I am sad.
Ashlynn: Why's that?
Jay: My Late Night Brain Syndrome is kicking in. All I want to do is sleep but I can't stop thinking.

Late Night Brain Syndrome by Nickkzor99 September 14, 2012

Fuck Buddy Syndrome 

The feelings of intimate, romantic attachment and closeness at least one of the two fuck buddies tend to usually develop.

Bob: Did you hear? Jafaar and Jasmine are fuck buddies now!
Obama: Yeah, I did! The lucky bastard, Jasmine is a fine piece of ass. Whatever, it won't last. Jasmine'll fuck anything that moves and Jafaar is way too clingy. He'll get Fuck Buddy Syndrome soon enough and she'll kick his ass the curb.
Bob: Too true. I hope Jafaar doesn't have any STDs because I'm planning on being next in line.

Fuck Buddy Syndrome by NipplePimpleMaybeBaby December 7, 2013

Barry Sanders Syndrome 

A psychological disorder in which an athlete is an excellent player on a team that fails to find any scrap of success. Named after Barry Sanders, an NFL running back who played his entire 10-year career with the woefully horrible atrocious Detroit Lions.

Example: Josh Gordon of the Cleveland Browns may be suffering from Barry Sanders Syndrome, as he is the only player on that team with a clue!

Barry Sanders Syndrome by Alaskan Pollock February 20, 2014

Save the Whales Syndrome

The belief that your niche cause is of such vital importance to everyone in the world that it’s your mission to force it on as many people as possible.

Ya, I know, just another case of “Save the Whales Syndrome”.

Save the Whales Syndrome by johnp May 2, 2014

Jesse's Girl Syndrome 

When a guy wants to date/likes a girl his friend is dating, from the song Jesse's Girl by Rick Springfield

Bill is friends with Jack, Bill has a crush on Jill and wants to date her, But jack Jack is dating Jill, Bill has Jesse's Girl Syndrome.

Jesse's Girl Syndrome by LJSmithNY June 15, 2014

Dick in the Butt Syndrome 

Otherwise known as DBS. When you have obsessive and compulsive thoughts about having a dick in your butt. This disease takes control of your life and brain, as it is literally the only thing you can ever think of.

Why are you sitting like that?
I have Dick in the Butt Syndrome. So it seems as though I have a dick in my butt, ergo I'm not sitting right.

Dick in the Butt Syndrome by Swiftus The Maxim March 26, 2016

Center of Attention Syndrome

Someone suffering from COAS is so pre-occupied with themselves and their issues that they have a hard time paying attention to anyone else. An extreme version of being self-centered narcissists, sufferers of COAS frequently don't know that they suffer from COAS, but they would love the idea that they suffered from an illness.

Yo! That girl totally suffers from COAS, Center of Attention Syndrome. She had no idea that my dog died because she was too focused on the drama with that bitch from her job. self-centered narcissist self-absorbed douchebag

Center of Attention Syndrome by India Golf Oscar September 20, 2016