A syndrome in which you are in desperate need of dick. Symptoms include: spaz attacks, constantly saying "I need dick in my life", and suddenly becoming a lowkey THOT.
Bonqueequee: "I think I have DDS."
Billie: "What's that?"
Bonqueequee: "Dick Deprivation Syndrome. I haven't had dick in a month. I need dick in my life."
Billie: "What's that?"
Bonqueequee: "Dick Deprivation Syndrome. I haven't had dick in a month. I need dick in my life."
by Ohyespapi July 2, 2017

An abnormality that affects nice good looking smart guys that prevents them from ever getting the girl or anything they feel that they deserve. They tend to help others but than the universe tends to screw them over for no apparent reason.
James: Hey, what did Sue say when you asked her out?
Sean: She said, "Awww, thats so sweet. I'll let you know"
James: That doesn't sound good at all man. Sounds like you just got friend zoned.
Sean: I figured. I assumed that if I helped her with her studies and brought up her grades she would finally go out with me.
James: Sounds like you have the Peter Parker Syndrome.
Sean: She said, "Awww, thats so sweet. I'll let you know"
James: That doesn't sound good at all man. Sounds like you just got friend zoned.
Sean: I figured. I assumed that if I helped her with her studies and brought up her grades she would finally go out with me.
James: Sounds like you have the Peter Parker Syndrome.
by monkeyd3128 March 1, 2012

In rare and unknown circumstances, the dick and balls disconnect from the body and fly into the sun, being known by medical professionals as Solar Penile Syndrome (SPS).
by wide idiot June 21, 2020

Or R.B.S. is defined as the thousand yard stare and overall uninterested, angry looking gaze that falls upon some women. Usually first diagnosed around age 20 it can both be genetic or influenced by ones environment to where the afflicted appears "bitchy" in absence of a smile.
by Nolin Chitwood February 15, 2015

A sad and mildly debilitating condition in which the sufferer will never be exceptional in a chosen discipline or field of study, no matter how hard they work. While incurable, it can often be treated/maintained with a reality check.
I'm sorry Mrs. Smith. You might as well stop your son's violin lessons. He will never be a virtuoso. He has chronic mediocrity syndrome.
by Blursaw March 1, 2010

An inability to throw out or sell old toys and/or objects from your childhood as a result of seeing toy story (1, 2 or 3), and thus having an overly sentimental view upon these objects and imbuing them with anthropomorphic qualities. Ultimately a dangerous syndrome when combined with those partial to 'Hoarding'.
John: Wow Dave, you really do have a lot of junk lying around your house, didn't you have a garage sale recently?
Dave: Yeah, i did, but when i looked at those little G. I. Joes i used to play around with i remembered all the personalities i gave them, and all the games we used to play...
John: Yes, but now you are 34 years old and do not play with them anymore, and they sit gathering dust in an increasingly over packed room where something useful could be
Dave: I guess so, i suppose i might be coming down with Toy Story Syndrome
Dave: Yeah, i did, but when i looked at those little G. I. Joes i used to play around with i remembered all the personalities i gave them, and all the games we used to play...
John: Yes, but now you are 34 years old and do not play with them anymore, and they sit gathering dust in an increasingly over packed room where something useful could be
Dave: I guess so, i suppose i might be coming down with Toy Story Syndrome
by Natsnud January 2, 2012

A drive to collect items of importance you find in Fallout 4 in real life.
I.E.: Globes for screws, Duct Tape for adhesive, aluminum cans for aluminum and/or any bottlecaps.
I.E.: Globes for screws, Duct Tape for adhesive, aluminum cans for aluminum and/or any bottlecaps.
Aw man I played Fallout 4 all weekend! Yesterday I saw a globe and something in me told me to go grab it so I could a screw from it, the same thing happened with a roll of duct tape just a few hours later! I think I got Fallout 4 Syndrome...
by Psymon The Cat March 9, 2016
