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conjunction of the phrase, "what is up?"
whaddup by ill bill December 23, 2002

Whaddup doe

another way of saying what's up, typically used in the Detroit area.
Hey, when you see him, tell him I said "Whaddup doe!"
Whaddup doe by wildfire98 April 6, 2010
What people with immense amounts of swagger say when greeting people.
Guy: Whaddup

Girl: Oh my god he's got so much swagger *melts*

Whaddupdoe? 

Whaddupdoe- interj. v. (whad-up-dough) is a colloquial greeting for "what's up though?", "hello", "what's up?" "Peace!", "hey!".

Through relaxed speech methods, this terminology originated in the streets of Detroit circa late 70's, early 80's.

Whaddupdoe can also be used in both exclamatory and interrogative forms.

Let's create a scenario...
Person A- Whaddupdoe Cuzzo?!? (another formal Detroit greeting).

Person B and replies back by saying "Whaddupdoe?"

Waddoup’d 

To be aggressively anally pentrated in the most violent way possible.
Ex: The girl was repeatedly waddoup’d and wondered why he didn’t call the next day.
Waddoup’d by BobGaveMeKnobSlob November 3, 2018
to ask a person how they are doing
hey girl, wadup?
hey, nothing just eating some grapes =)
Wadup by MegStephanie July 5, 2006