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Based on the battle record of the evil Decepticon leader from 'Transformers', Megatron means to wreak havoc when able, but to turn tail and bitch out at the first sign of adversity.
A: "I own this map!"

B: "We're making a comeback!"

A: "Fuck, I quit!"

B: "Fucking Megatron."
megatron by diabolicuss July 19, 2009
A penis that exhibits the "grower" characteristic of significantly expanding and lengthening upon erection as opposed to the "shower" characteristic where it is already near maximum size at rest and does not get much bigger upon erection.
Hey, baby. How you doing? Don't be fooled by the Decepticon in my pants. My Megatron is full of destructive force capable of making you/your Starscream.
Megatron by BaboonKiller December 8, 2013
Hit single by international superstar Nicki Minaj. Megatron
Wow Sis! Megatron by Nicki Minaj is a bop
Megatron by YesBitchImmaChica June 29, 2019
Nicki Minaj's new song
Someone: Hey the new song by Nicki Minaj?
Y/n: Oh Megatron! Yuh it's lit
Megatron by idc👑 June 23, 2019
Anal penetration, with no warning, no luracation, or condom.

origin; Holyoke Ma.
Don't make me megatron you!
Megatron by Clyde Harper February 8, 2009
Something that is huge or really big, usually used as if something is really bad (because Megatron is the bad guy in Transformers)
Man, I had a megatron exam in math, and I'm sure I bombed it.

That guy is a megatron douche!
Megatron by Cerpin Taxxt October 28, 2006