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Im Duffed Out 

Im Hella faded right now i dont know how im going to make it home tonight. i dont even know where the fuck i parked at. I'm Duffed Out
You tryna get Drunk today im Duffed Out.

Arthur Duffed

It’s another word for when someone or something falls over or dies
Person 1: My dog puid just Arthur duffed, now he’s in the quantum realm.

Person 2: So sorry to hear about your dog. I hope no body else Arthur’s in your life
Arthur Duffed by Vpcarson1 April 29, 2024

Tweedle Duffer

Someone who goes into the jungle gets bitten by a tick or denge bug and catches a 5 day fever AKA jungle fever
I held on to the antibiotics incase I met sombody who would be such a tweedle duffer as to run though the jungle with no bug spray on.
Tweedle Duffer by DemonWeapon April 14, 2017

stuffin the duffel bag 

when you fist fuck a girls pussy and ass at the same time.
she is all stretched out. i was stuffin the duffel bag last night.

Duffers' Syndrome 

A slang term for the very serious medical condition duphershypertrophy whereby the sufferer acquires over time excessive fatty tissues to the nasal region, giving the patient the not unpleasant features of a gnomish looking fellow; rosy cheeks from the strain of holding one's nose up all day, at times somewhat gormless facial expressions (which can be attributed to the drag-factor but more often can lead an innocent bystander unaware of the condition to conclude that the sufferer is possibly some sort of simpleton) and of course the ever-expanding, bulbous nose which grows and grows like in that fable about the enormous turnip...

Prognosis: Not good; rhinoplasty recommended.
What are you doing resting your nose on that snooker cue? Have you got Duffers' Syndrome or something?
Duffers' Syndrome by Mouldy123 April 3, 2011
to duffet: (duf-it) to screw someone out of their money, in snakey type manner. To not pay money to someone that you owe monetarily. To get work out of someone without paying them.

*The people getting screwed are of no significance even if family or friends.
fuck me. I worked with that motherfucker for a week and he duffeted me out of $300. Never gonna work for that cheap douchebag again -_-
duffet by garbanCHIC May 4, 2008