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The Best medical college in the south and east of the Mississippi. Has one of the best coach in the world (coach K). Founded by tobacco farmers. Tuition is about $40,000. School for the rich and the really intelligent. A private school. has the biggest rivalry in all of sports history with UNC. Also, contains the best Hospital in the southeast. Has National Titles in mens basketball in 91', 92' and in 01'. Definetly a school for the ones who want to succeed in life.
James: Do u go to Duke?
Alfred: Yes i do
James: U must be really rich and smart.
Alfred: Well i drive a Ferrari and got a 1600 on the old SAT.
James: Well ur at the right school.
Duke by SupraCelica27540 May 21, 2005
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"Are you a UNC fan?"
"Hell naw, I'm a Duke fan."
Duke by Laurie *is hot* April 9, 2005
1.A fist, plurally said as dukes meaning two fists
2.The act of striking a person or thing with a fist
1.Put up your dukes
2.That punk was talk'n shit so I duked him in the head
Duke by Grant106 May 15, 2005
uh like the best fucking basketball team there is? duh
djdkdkdkdkdkdlsl dk dkl
duke by sdklfj April 3, 2005
the poorest, most pathetic excuse for an institution of higher learning to ever disgrace the earth; a location approximately 7 miles from the number one university with the number one basketball team in the nation - UNC; a location where individuals who are too ugly to be functional society members are sent for isolation
Everyone who goes to Duke graduates gay and wishes they had gone to UNC.
duke by Stephanie February 21, 2005
basicilly a kid with a huge dick. looks great, smells great, and all the ladies want him. great at sports also. great sense of humor.
he ashualy dit it. Duke is such a stud
Duke by Anonymau5ee January 3, 2011
(verb) to completely ignore people's IM's and make up bs stories the next day when inquired. People are especially duked when the person is:

1. doing acadec work
2. catching 'em all.
3. staring at his physics book with passion
4. frustrated from not being able to catch magikarp
5. reading the latest reviews on the newest pokemon game
6. memorizing all 151 original pokemon names
cool duck
victim of duke-hey, why didn't you respond to my IMs last night?
duke-r-oh, uh, I was afk catching charmander.
victim-you already caught him on Diamond, dude
duke-r-yeah, but not on Fire Red....
duke by number1coolduckfan May 11, 2010