Semantically in some contexts, the colloquial nomenclature and noun is a derogatory accentuation of the "sluttishness" of a female's demeanor or disposition or both. In other
words, a woman who fornicates frequently with different recipients and has several sexual relationships.
The nomenclature "thot" can also be utilized and assimilated as an acronym: that
hoe over there or, equivalently, that
prostitute over there.
In some situations, the acronym is misused and applied. Typically, the term, as an acronym or
non-acronym, is used to entail the interpretation that the concerning woman is sluttish or "slutty" (regardless of veraciousness or correct usage).
The informal term is frequently used and seen in
memes and social media.