LIS simply stands for laughing in Silence. For all of you who have the addicting thing called myspace, use LIS instead of LOL.
by Kirk Kaubish April 16, 2006

An abbreviation for Long Island, NY.
by Harry Stotle January 19, 2008

man: hey stopping telling lies, thats bad!
child: actually you will find that they are the future, as am i
child: actually you will find that they are the future, as am i
by Satan with a Perm June 24, 2010

by Rex Norman November 28, 2021

by MK JJ HB December 9, 2008

Laughing Internally. Used when texting/chatting online and someone says something kinda funny but not funny enough to make you laugh out loud for real so you type LI instead!
Person #1: Hey, did you see that old man @ the store today??
Person #2: Yeah his pants were really up high. LI
Person #2: Yeah his pants were really up high. LI
by iwasbored September 1, 2010
