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inbreeding 

The breeding of people/ animals/ plants that are closely related to each other (first cousins or even closer), thus keeping the genepool weak and leaving them vulnerable to various health problems, mentally and emotionally as well as physically.
Purebred dogs and royalty are notorious for inbreeding; to keep the line "pure" then they are only allowed to procreate with their "own kind", even when offspring are stupid, sickly, deranged, ugly or any number of things.

Carlos II of Spain was the end result of the Spanish Hapsburgs; his parents were uncle and niece and both were highly inbred. Carlos was deformed, retarded, delicate, and had an extended infancy and premature senility. He was married twice, but he was impotent and sex was beyond his abilities.

Plants can be inbred, too; bananas of today are very different from those of three generations ago and often lack the genetic diversity which would keep them healthy.
inbreeding by Lorelili January 17, 2011
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Inbred Pittsburgh 

A resident of Pittsburgh, PA who has a high likelihood of being born from inbred bloodlines, as the Western part of Pennsylvania is in the heart of Appalachia. Appalachia is known for extreme poverty, low IQ, poor hygiene, and inbreeding with close blood relatives.
I'm going to have to stay in my hotel tonight where its safe so I can stay away from the inbred Pittsburgh residents. I don't want to come in contact with those people, I don't want to catch a disease or lower my IQ.
Related Words

Incredible Hulked 

When someone passes out drunk at your house ( or any house or place ) You and friends drag them in the woods take their shirt,shoes and socks off then you cut their jeans or pants into shorts and they wake up thinking they turned into the Hulk. You get mad at the victim when you see them again and tell them they turned into the Incredible Hulk and fucked your house up!
Man dude what happened? I woke up in the woods without half my clothes! Dude don't get mad at me you are the one who turned into the Incredible hulk last night! Shit you incredible hulked me!!
Incredible Hulked by moman86 November 2, 2013
One who's family tree goes in a straight line.
Please don't search "Inbred"on Google Images...
Inbred by Ben Reave April 5, 2012

Inbred Dickwad 

The horrendously offensive insult screamed at you by the cops in GTA Online
Inbred Dickwad by Scrawny Nag June 15, 2020

Incredelicious 

Incredibly delicious. Not to be used outside the description of foodstuffs, 'incredelicious' is a word reserved for the most decadent of cuisine.
These cupcakes have been made to perfection. They are *pause to emphasize the enormity of such a statement* incredelicious.

He just kept talking in one long incredibly unbroken sentence moving from topic to topic so that no one had a chance to interrupt, it was really quite hypnotic 

Captain Jean-Luc Picard of the USS Enterprise
Captain Jean-Luc Picard of the USS Enterprise
Captain Jean-Luc Picard of the USS Enterprise
Captain Jean-Luc Picard of the USS Enterprise

???

He just kept talking in one long incredibly unbroken sentence moving from topic to topic so that no one had a chance to interrupt, it was really quite hypnotic (hypnotic...)

Incredibly unbroken sentence moving from topic to topic