by faggotskillgays December 6, 2016

Stacy was just a bartender at Applebee's when she met that basketball player. She snagged the ultimate come up.
by Sidewinder01 September 19, 2012

by Ellekaybe January 1, 2015

by TheKidB September 1, 2013

The time from when you first take a drug, to when you reach the first peak of the trip/roll. Usually the first 30 minutes to 2 hours depending on what drug taken, and the person.
by lsdmdma69 May 24, 2010

Slang for a plan to steal as much money as possible from somebody to avoid being on the street straight out of prison.
I’ll be coming up good and fast as soon as I get out, it’s sheer genius and it’s all mapped out to perfection.
by Dr Bunnygirl February 24, 2019

The Come up is the period of time when the drugs that one has taken (usually psychedelics such as LSD) are beginning to take noticeable effect. Normally referred to as the first stage in a trip before peaking.
by doowre April 14, 2017
