by iecfbaili April 29, 2007

Taking a handful of Tylenol PM and then trying to have an orgasm before you fall asleep. Something that has been rumored as impossible by old people everywhere.
Hayden- "I just did 50 pull ups!"
Luke- "Please, I have completed the Tylenol PM challenge the past three nights in a row."
Hayden- "Nigger please, your shitting me"
Luke- "Please, I have completed the Tylenol PM challenge the past three nights in a row."
Hayden- "Nigger please, your shitting me"
by Cool_Hand_Luke December 1, 2013

by THE Tylenol PM Bitch =P October 12, 2008

A hardcore illegal drug in which you inject your own feces into your penis hole in order to increase chances of herpes.
by big titty bitch January 22, 2005

by Cody5050 January 27, 2022

by ShallowWaters September 25, 2025
