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1. An adjective meaning awful, horrible, or the worst. The opposite of 'the shits' is 'the shit', used to describe something that rules or is generally really awesome. 'The shits' generally refers to something that sucks to just short of the greatest extent possible.

2. Another word for diarrhea. You get the shits when you eat something that makes your feces take on a primarily liquid form.
"Man, Weenus's breath is the shits. I can't believe I let him hiss right up my nose. It's so disgusting but I just can't stop."

"I sure wish I hadn't eaten all that rat shit. I think I'll have the shits for the rest of my miserable life..."
The Shits by American Jesus January 9, 2004
I shouldn't have ate Indian food before i had anal sex. I had a bad case of the shits all over his peenieweenie!
the shits by Nicolley August 2, 2006
Used with the verb "to have"

To be missing in action for an extended amount of time without explaining. Popularized by The Trooper.
Where is he? Does he have the shits?
The shits by Numen March 8, 2007
Diarrhea with such a ferocity so you don't want to know about it.
After I ate my brothers old cookies, my ass switched to Defcon One at contact with the shits and I crapped myself while running down the stairs to the shit-station.
the shits by Ali. S February 22, 2007
"you give me the shits", "i've got the shits", "that shits me", "that REALLY shits me", "you shit me", "it's really shitting me right now", "what a shitter", "i've had a shitter of a day".
the shits by John Phillip July 31, 2006
soggy/lumpy substance passed through the arsehole pretty much always smells like a family of badgers have died up ur arse a month before release also see townie
damn i think that curry gave me the shits
look at those townie shits
the shits by mark innit October 27, 2003