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Mofo Meaning : motherfucker but in a word you can use around parents and or teachers!!Explaining someone who is a real annoyance and/or cocksucker and/or beotch
Stephanie:That Devon is a real mofo , I dump him and he says he dumped me !!

Nick:Yeah it's about time you dumped his sorry ass!!
MoFo by White-and-Nerdy January 6, 2007
A mofo is the biggest cocksucker in the whole world such as my friend Neaku, who has men up his butt constantly. A mofo is also a person who always spreads rumours about you like a little bitch
That mofo’s a Fag
Mofo by Travis-Scottgod May 29, 2019
Short for Motherfucker = someome who is ridiculously awesome. Also, (30 Seconds to Mars') Tomo Milicevic's favorite word.
That Tomo is one crazy mofo! Have you seen him play live? Amazing.
mofo by thevenomousone February 26, 2010
This dumbass mofo ain't gon' do shit!
mofo by Laqueefa May 14, 2005