"fo shizzle ma nizzle" is a bastardization of "fo' sheezy mah neezy" which is a bastardization of "for sure mah nigga" which is a bastdardization of "I concur with you whole heartedly my African american brother"
by pixelfrenzy April 15, 2009

1. For Sure, My Nigga'. Commonly played out by snoop dog and other rap artists. Found Irefuetably aggravating for the southern , blue collared working class, white american.
Fo Shizzle Ma Nizzle, lez go smokkee some weedz
by matt June 8, 2004

by harv1989 October 24, 2006

This is not a word, period. It is some silly bullshit perpetuated my Snoop Dogg or P. Poodle or whatever he is calling himself this week. However, if you really want to judge it to the same standards as real words, it loosely means "Okay".
by Gunsl1nger <www.global.genericwebhost.com> June 7, 2004

by sah January 30, 2003

by G-unit princess February 17, 2004

by funky nOok February 24, 2003
