'Pick Up' is a
beautiful phrase with various meanings.
The ones most often used are to successfully
score with a girl via some line or to get
drugs.
In this version, it means to generally do good. If someone needs to get something done fast, they need to Pick Up, or if they say they're going to talk to someone they fancy and that person comes along then they need to Pick Up. More or less it means to just get something done.