"Big Smoke" often refers to a large amount or extreme amount of smoke a person blows out, exhales, during the process of smoking.

Big smoke is a term used when two (2) or more people gather as a group, in a room, a car, or any place that allows smoke exhalation, (blowing big smoke), to be most visible.

When illegal drugs are used to get high, using the method of smoking the particular drugs such as meth or marijuana. Usually done from a oil burner aka meth pipe, rolling paper, bong, aluminum can, etc. Followed by observing of the amount of smoke in the room.
"We blew so much big smoke in his truck on our way to the casino, that when we opened the doors, the truck looked like it was on fire!"
by GiGi1111 June 11, 2018
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A guy from GTA
Big Smoke: I'll have a number nine, a number nine large, a number 6 extra dip, a number seven, two forty-fives, one with CHEESE, and a large soda
CJ: Fat boi
by Trisced1 August 24, 2019
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A Large Obese Black Individual, Usually Accompanied By A Hunger For Hamburgers Or Excessive Amounts Of Edible Materials.

Including Ass.
DAMN, THAT NIGGA IS A BIG SMOKE, HE ATE THAT WHOLE ASS
by Niggaslayer69 July 19, 2019
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A ghetto term for when a collective of teenage individuals engage in smoking.
Yo boys, its time for The Big Smoke
by cuse-stoner420 September 17, 2019
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One of the Grove Street Families in GTA: San Andreas. Quite a funny character but as the game progresses you discover that him and another fellow GSF gangster, Ryder are selling and shipping drugs with the enemy gang.
I can't believe that BS would sell out on his homies.
by Craig April 20, 2005
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