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A common insult thrown at people by Bostonians. This can be used both as a term of endearment, or a backhanded comment to go fuck yourself. Often times the latter, rarely the former.
“Hey how’s your mum doing? Rocked her world last night”

“Yeah Jeff? Blow me loser
Blow me by John from Southie October 9, 2022
Your about to blow me
blow me by Shake some ass April 6, 2023

Blow me down 

Blow me down.”
is used to express surprise.
"I could ask Squire for some.”
“Without Captain knowing?”
“I'm sure I could.”
“Blow me down, so ye could.“
Captain Flint in the movie “Treasure island”, UK/USA 1950

blow me like a trumpet 

A nifty phrase you can drop in the workplace that is sure to offend the ultra tight-ass crowd who have difficulty with crude references to body parts or sex.
Why of course it was entirely impulsive, inappropriate and sadly unprofessional for me to state, “well they can blow me like a trumpet!” - I should have better assessed my audience!

Blow me up Tom 

"Blow me up Tom" is the official exit of callers on the Tom Leykis show, a syndicated national radio program that airs in the afternoon/evening. The request is followed by an explosion sound and then the call is terminated.
That's all I have to say, thanks for taking my call. Blow me up, Tom!
Blow me up Tom by BMcC August 28, 2004

Blow me where the pampers is 

Originating from the 1994 movie: PCU. This term is most used as a comeback when someone says or does something you dislike. Can be used just like: "blow me" but adds that extra bit of urban flavor. This saying will often confuse and insult simultaneously.
Dude 1: Why did you order cheese on my burger?

Dude 2: I went and got it, didn't I?

Dude 1: So?!

Dude 2: So! You can "Blow me where the pampers is!"