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the acronym for what you say to someone (shut the fuck up) who spells internet acronyms out loud in a real life conversation as opposed to saying the actual words.
dude1: stfu (spells out stfu) I only kiss that other guy cause uh..it's my religion so wtf (spells out wtf) you talking about I'm definitely not gay.

dude2: dude YOU shut the fuck up you cant even speak proper english and that was the dumbest bullshit I've heard since I saw George Bush on Global National.
stfu by tony chen December 15, 2008
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The word some noobs commonly get mixed up with Stuff You!
John: I got the last lolly pop!

Francis: STFU!!!!!!

John: Stuff you to yourself!

Francis: o.O
STFU by Dodgy-deeds July 7, 2011
In NGC's book, stfu is when he drops something, or if he won, or both.
|09:39| »» +Neo_Genocide_City for the final time
|09:40| »» +Neo_Genocide_City STFU
stfu by Gunner112k August 21, 2003
It means for Tsuki to stfu plxkthxbye.
Tsuki STFU, plxkthxbye.
(j/k)
STFU by Flare17 September 16, 2008
Luke: What are you doing later?
Josh: Stfu
Luke: Nice!
Stfu by blank blank March 29, 2015
Kwame has been disturbing since morning,will someone tell him to "stfu".
stfu by milady June 8, 2015
stfu means you should stop whatever that you are doing or you shouldn't be doing that bro.
stfu by TheFuckingUrbanGuy September 12, 2015