YouTuber’s disease

(NOUN) to destroy one's reputation of a YouTuber.

“Unfortunately, like most Youtubers, he caught Youtuber’s disease”

by Mr. Gupta August 8, 2023

Holmes disease

When you have an above average penis size.

In reference to John Holmes 🤘🏻

Wife:That's my husband TYLER LEE!

Random ex- metal bandmate: FUCK YEAH! MY BOY, HE HAS HOLMES DISEASE! His stage excitement could be seen for miles!

by TychelleMoffitt1999 December 12, 2023

Japan Has No Sexually Transmitted Infections Or Disease so Try To Kill, Angel Jose Robles, Also Known As, Hellstrom, Hellstromism, Hellstromismu, Holi, Holism, Holismu, And Messenger Add Oak In The Bronx

Japan Has No Sexually Transmitted Infections Or Disease so Try To Kill, Angel Jose Robles, Also Known As, Hellstrom, Hellstromism, Hellstromismu, Holi, Holism, Holismu, And Messenger Add Oak In The Bronx

Japan Has No Sexually Transmitted Infections Or Disease so Try To Kill, Angel Jose Robles, Also Known As, Hellstrom, Hellstromism, Hellstromismu, Holi, Holism, Holismu, And Messenger Add Oak In The Bronx

by TheSpartanicaOfAnyHellstromu3e April 9, 2025

Kyah Disease

Attraction to women with bent wigs or crooked lace-fronts.

Damn that wig sitting up but she still fine. I think I got Kyah disease.

by Kemistry🌟 May 28, 2024

jess disease

When the Pokémon Jess has spread her sicknesses though technology and Air the way to cure of this to contain her or take care of the sickness you have of it

“Oh SHET JESS DISEASE KILL HER”

by Jessfallenangel September 17, 2019

human fly disease

The condition that a human fly suffers from.

Damn, you'd think she'd leave me alone after I rejected her 10 years ago.

Maybe she has human fly disease?

by humanflymagnet February 8, 2010

PGR Disease

PGR or "Prettiest Girl in the Room" Disease is a condition that afflicts attractive women everywhere. It's characterized by the negative reaction a pretty girl expresses when she meets a girl that's prettier than her, rendering her "not the prettiest girl in the room" anymore.

Girl 1: Mandy, you look lovely as always. I'd like you to meet my friend, Sexy Withoutmakeup.

Girl 2: I don't like her.

Girl 1: You just met her, why not?

Girl 2: She's dressed like a whore.

Girl 1: Oh, you're just being jealous. You've got PGR Disease.

by rhastings88 March 3, 2014