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OMG ISS

When somebody says something really stupid,OMG ISS is what you should reply with. It stands for OH MY GOD. I'M SO SURE!
Drunk guy at the bar "Will you pleeaaasse take me home with you?"
Michelle "OMG ISS!"
by Sosure March 24, 2010
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OMG Syndrome

A disease-like state of feelings which can only be discribed as "OMG!"

Typically occurs when:
1. Ones mind is blown
2. Exciting news/gossip is discovered
3. Something unbelievable happens
Girl 1: "I'm suffering major OMG Syndrome right now..."
Girl 2: "Why? What happened?"
Girl 1: "I just found out that Mitch and Kaylee have something going on!"
Girl 2: "OMG! REALLY?!"
by C3POhbaby January 9, 2010
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OMG-S

Oh My Goddess! Used in the same context as "oh my God" but as an alternative for those of us that seek another path
OMG-S That love spell worked alil too well
by The Lady Rowan July 2, 2012
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omg armyonces

a phrase used by armyonces when even the smallest interaction occurs within bangtwice
1: bts just danced to shy shy shy!
2: omg armyonces!
by omgarmyonces May 14, 2020
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OMG Room

This is a room in everybody's house where they keep the door closed because this is where they put all their junk that they don't know what else to do with it. So when you open the door the only thing you can say is "Oh My God".
Friend#1:What's behind that door?
Friend#2:Oh that's my OMG room.
Friend#1:Well let's have a look.
Friend#2:OK
Friend#1:Oh My God!
by Mojo maniac October 6, 2008
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OMG NTP!

OH MY GOD NO TOILET PAPER!

The horrifying realization there is no toilet paper after a significant bowel movement.
texting: had to take emergency sit down at Wal-mart. OMG NTP!
by dintx August 22, 2010
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OMG it's big!

"OMG it's big!" or "OMG it's huge!" (OMG acronym for, Oh My God!) A quote commonly used by females to describe a big penis usually when seen for first time. Though, statistics show most females use the phrase when seeing a big arachnid (like spiders.)
*Girl looks in huy's pants* OMG it's BIG!"

*Your mom sees a spider* AAAAAAHHHHHHH!!!!!!! OMG IT'S HUGE!!!"
by MC ST0RMPEGASIS September 24, 2016
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