by Peter Buttram, Proctologist/Asstronut August 11, 2006
What is irritating that person that they are so annoying you don't want to be around them.
The other way to define it is "What's crawling up your ass!"
The other way to define it is "What's crawling up your ass!"
by JillsCrazyPlace February 03, 2010
A dismissive way to answer someone annoying you for help, or just to be an asshole. Especially useful at work.
"Where can I find the foot-long dildos?" "Up your ass & to the left."
"Did you get that memo from the staff meeting?" "Yeah, it's up your ass & to the left."
"Did you get that memo from the staff meeting?" "Yeah, it's up your ass & to the left."
by Dharma Midget December 16, 2019
Milsey approaches liss and says hey liss what are you doing.
Liss ignores milsey and milsey then says "What is up your goat "?
whats up your goat?
Liss ignores milsey and milsey then says "What is up your goat "?
whats up your goat?
by liss_misley_mad January 13, 2012
by Yep, I did it, so what? May 05, 2016
by bobbyt June 17, 2006
by Zoe89 December 02, 2009