A drug combination as featured in "Get Him To The Greek" released in 2010. Showed as rolled into a joint. The cornucopia of drugs includes, but not limited to: Marijuana, Opium, Heroin, Peyote, Cocaine, and other unidentifiable substances.
Sergio gave The Jeffrey to Aldous.
by Phanteh June 8, 2010
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a mammoth joint filled entirely with an assortment of drugs. marijuana, opium, angel dust, meth, painkillers etc. Half of the ingredients are unknown, but one things for sure, it fucks you up.
Bro: dude take a hit of this you'll be fine.
Scro: I dunno man, I guess so.

*smokes jeffrey*

Bro: yoooo what are you doing calm down!
Scro: My hearts beating fast, whats in this jeffrey even?!
Bro: I don't know dude, just rub a furry wall you'll be okay.
by fattehboi June 5, 2010
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really gay and not smart probably the stupidest person you will meet.
jeffrey is so dumb.
by chaboiskinnypenis December 12, 2017
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hansom smart ravenna student that is very populer
jeffrey is so hansom
by jonathin the 69'th November 14, 2018
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Someone characterised as being narcissistic, self righteous and proud, often regards them self higher than others and are sore losers
by Myrtleboo October 14, 2018
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Lame Fat Dude: Uh, guys? What is this stuff? My heart's going really fast.

Cool British Dude: Oh, it's a bit of this, a bit of that. It's called a Jeffrey. It's mostly weed, with a bit of opium as well... ground-up E's... heroin... Clorox...
by Raeper142 October 15, 2010
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