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The Mr. O'Brien Science Brainrot is a subculture, religion, manuscript, and "disease", based on the life of Russell O'Brien. Due to his high-pitched voice, a voice recorded file of a Mr. Hanky soundin ahh fella went viral within New Zealand, bringing the group into popularity.
"William and Arman's conversion to the Mr. O'Brien Science Brainrot group changed my perspective."
"The legend of O'Brien's breakout of an ISIS facility through rat atom manipulation inspired me to convert to the Mr. O'Brien Science Brainrot"
by Bigwillyoftingletribe April 24, 2025
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Brainrot

Learning the ways of mythical rizz of the brainrot.
Fanum used his brainrot to seduce livvy dunne.
by skibidiitolietwillbemine May 29, 2024
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Brainrot

a term commonly used in memes (such as Italian brainrot)
You watch too much Brainrot.
by totallypolites;) July 12, 2025
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Brainrot

by Dr. Seuss II December 19, 2024
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Chronic Brainrot Syndrome (CBS)

A modern condition caused by excessive exposure to TikTok, Reels, or short-form content, leading to mental “brainrot”—characterized by a cluttered mind filled with useless trivia, viral sounds, and fleeting dopamine hits. Symptoms include decreased attention span, compulsive scrolling, and quoting random TikTok audios unironically.
I needed to study for the finals tomorrow, but instead, I was scrolling on TikTok and IG Reels for several hours because my Chronic Brainrot Syndrome (CBS) was flaring up. Now I can’t stop humming random TikTok audios while panicking about my notes.

My Chronic Brainrot Syndrome (CBS) kicked in hard last night. I spent four hours watching IG Reels about cats instead of finishing my project.
by Aflbck December 19, 2024
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brainrot syndrome

all you do is shitpost braindead brainrot content like an gen alpha ipad kid
by SCPlayz7000 April 21, 2024
mugGet the brainrot syndromemug.

Brainrot

When a popular meme or a popular term gets taken too far.
Steve: “Wyd bro?”
Tom: “Watching Duke Dennis get girls with his unspoken rizz 😍”
Steve: “Brainrot”
by Crankdatsuperman May 7, 2024
mugGet the Brainrotmug.

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