The worst Karen there is. Most Karen's ACT like they are autistic, but autistic Karen's take it to a new level. They are the kind of people who would ask for the CEO
Person 1: Did you see that Karen ask for the manager?
Person 2 : Yeah, they must be an Autistic Karen
by PythonCZX June 3, 2020
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One of the plastics in the movie Mean Girls. Is described by Damien as being "one of the dumbest people you will ever meet". Claims to be able to predict the weather using her breasts. Played by Amanda Seyfried.
"If you're from Africa, why are you white?"

- Karen Smith, 2004
by Thats16myboi July 24, 2020
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The type of upper class woman (usually a bleached blowout blonde) yelling at minimum wage employees because she can't return an expensive item with no tag/receipt. Unaware of class struggles and pain of marginalized groups. Collagen lips and plastic surgery paid for by rich (but absent like her own rich and absent father) husband.
Collagen Karen: OMG! How dare you not allow me to return these Prada sunglasses even though I ignored all the store's policies! I need to speak to the owner of the building- What's your name?? Lemon?!

Employee : You're a grown woman throwing a tantrum, ok Collagen Karen.
by heyworl June 8, 2020
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Of any Caucasian woman with a bob cut replaced with Karen now.
Friend: I love your Karen hairstyle, Jenny.
by Dada Philosopher April 26, 2020
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The biggest asshole of all the assholes. Mean spirted. A social media bully coming to you from moms basement. They are always right and blame everything wrong in the world on Karen. Racist; Karen. Someone is wearing a mask; Karen. Someone is not wearing a mask; Karen. They don't agree with you; Karen. Someone is acting entitled; Karen. My asshole is sore; Karen.
Billy Bob: I wonder what q group Karen's talk about?

Karen: They talk about how the world is full of asshole Karen bashers. Hey, did you know that the male version of Karen is Billy Bob?
by Karen's united January 8, 2021
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