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What's up

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An excuse for your friends to be dickwad punsters when you just want to hang out.
A-Hey what's up?
B-The sky!! hehehehe
A-Fuck you, Thomas
by j00j00 May 31, 2015
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what's up your butt

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It basically means: "Why are you so mean/angry/salty today?" In my understanding...
"Go away," he said angrily.
"Jeesh! What's up your butt today?"
by Can_u_not April 18, 2016
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what's up

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A question that means "hi" or "What are you doing"
It can get annoying, but people don't seem to understand that.
The best way to answer is "I think it's the opposite of down" if you are annoyed by this question
"What's up?"
by The Billionth Random Monkey December 15, 2014
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to be muttered directly after a sweet comeback.
you: are you really gonna wear that?
me: yeah. it's better than that frumpy-ass clown suit you got on. WHAT UP SHUT UP!
you: damn you got me good.
by LDAWG9 February 6, 2008
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Thats wats up

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Something someone says whenever anything happens and they want to kill the vibe.
Malcolm: This guy likes you
Girl: Sorry I'm talking to someone
Eleazar: Thats wats up
by Tennis Squad April 18, 2013
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1. A casual greeting or conversation starter, somewhat of a rhetorical question.
Usually followed by something like "Not much, you?," "Nothing much," or even answered with a "Hey man, how's it going?"
syn: How's it going? What is new?

2. syn. What can i do for you?, What would you like? What's on your mind?
1. Person #1: Hey There! What's up?
Person #2: Oh not much. What's up with you?

2. Person #1: Hey come here for a second, I have to ask you something.
Person #2: Ok, what's up?
by GangstaRL December 28, 2005
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What up ho/hoe

A pleasantry, often used to greet a friend.

The "what up" may also be used in conjunction with "slut" or other suitable words which may not be found offensive in this particular usage.
- What up ho? How was the party last night?

- What up slut? Down to play some videogames?
by The Goobinator September 8, 2013
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