An annoyed or embarrassed response to the stupidity or incompetence of another. Synonymous with "Shut the fuck up", or "Jesus, you're stupid". Derived from one man's inability to counteract the obliviousness of those around him, to which he blurted it out in frustration. Also, an appropriate reply to an unfunny or otherwise retarded joke.
by Captain Walleye August 20, 2008

by AlPacino1972 August 3, 2014

A phrase used by a male, to communicate, to a significant other, that he wants some ass; Back it up on his dick. Give him the booty.
by JeiOfExodia June 18, 2020

1. Greeting to someone. A way of saying "hey what's up?" origniated in Detroit.
2. Can be used as a term of aggression to entice someone into a fight or altercation; Bring it on...
2. Can be used as a term of aggression to entice someone into a fight or altercation; Bring it on...
1. Guy sees his buddy and greets him with " What up Doe?"
2. Guy 1 walks into a bar with the mean mug, staring at guy 2. Guy 2 throws up both hands and says "What up Doe!?"
2. Guy 1 walks into a bar with the mean mug, staring at guy 2. Guy 2 throws up both hands and says "What up Doe!?"
by Most_ill December 5, 2009

Refers to being so busy that you don't have time to use a restroom.
Used in the context of passing someone who wants to chat and you do not have time.
Used in the context of passing someone who wants to chat and you do not have time.
Cher: I swear, ever since I had Sonny axed, it's been non-stop busy for me.
Sting: Bloody hell! Know what you mean. Ive been running so much this week, I have to shit standing up!
Sting: Bloody hell! Know what you mean. Ive been running so much this week, I have to shit standing up!
by Richard Halliburton, Jr. December 29, 2007

If someone is acting really stupid or crazy, they need their medication increased to calm them down or make them more at ease. Can also be use to describe a person who is acting stupid or silly.
Can also be :Up Your Dosage, Up Their Dosage, Up Her Dosage, Etc.
Can also be :Up Your Dosage, Up Their Dosage, Up Her Dosage, Etc.
Joe:"Wow, He is acting really wild."
Sam:"Yeah, I guess they need to up his dosage. Keep him calm, or something."
Joe:"Get him some Prozac."
Sam:"Yeah, I guess they need to up his dosage. Keep him calm, or something."
Joe:"Get him some Prozac."
by Scott Iorillo March 16, 2007

1) To exert much effort but still fail miserably
2) Fall short of a goal
3) To get busted, caught red handed
2) Fall short of a goal
3) To get busted, caught red handed
1) It took him years to save all that money only to get it all stolen. That's what he gets for hiding all that cash in his house instead of putting it in the back. What a way to come up short!
2) He was banging this married chick. They were at her house fucking and her husband came home. Her husband was a cop! That guy came up short.
2) He was banging this married chick. They were at her house fucking and her husband came home. Her husband was a cop! That guy came up short.
by NLL November 11, 2005
