Jake Paul's Disease

If you're watching Jake Paul's ass-giving, shit-living videos, CONGRATULATIONS! I'll see in you're funeral!

Max: Jake Paul's videos are sick!
Dr. James: Of course they are! You're infected you tiny bitch! It's called Jake Paul's Disease!

by Why the fuck are you reading? November 9, 2018

Macaroni Penis Disease

Closely associated with peyronies disease.

Macaroni penis disease most frequently occurs as a side effect from Russian Macaroni

Last week my friend was diagnosed with macaroni penis disease. He thinks he got it from the Russian macaroni party dip.

by Electric Joe August 22, 2018

Tu-Sty Disease

The unfortunate act of loading the toilet paper roll incorrectly, which causes the toilet paper to be dispensed under the roll. Symptoms present are absence of common sense, inability to understand the obvious repercussions of the act, and irascible guests to said home individual resides in. May cause loss of friends, loss of IQ, and loss of bathroom priveledges.

Cause: unknown

Cure: a swift kick to the face

Bro 1: I broke up with my gf today, bro.

Bro2: Bro, why?

Bro 1: she has Tu-Sty Disease, bro. I can’t love someone who could infect me at any second.

Bro 2: oh fuck that, bro. Good choice. Bitches be crazy.

*Bros high five and continue to walk to their dads boathouse in their Patagonia’s, chubbies and boat shoes*

by Stuckonpuck September 9, 2018

mark waters disease

Mark waters disease also known as Mark waters disease

Mark waters disease is a form of disease and not a disease example you got Mark waters disease

by Sinotyrannus November 17, 2022

motor neuron disease

A "Disease" which is not even a disease. An illness that gradually destroys the motor neurons in your body. Eventually the sufferer wont be able to do anything. The Hollywood actor, David Niven had the "disease". There is no known cause of the illness, nor a cure, but there is research going into the prospect of using stem cells to recreate the savaged motor neurons, but it's not yet known if the disease will destroy the new ones too. Has nothing to do with shakey hands.

My dad had trouble walking, he went to the doctor for tests. He later found out he had motor neuron disease. A while later he got pnumonia and died 3 days after christmas day, and I was 12!

by christ0pherjack December 28, 2005

Chris Ryan Disease

The medical condition when one is so sexually attracted to a black woman that he will throw himself onto her in a sexual rage that cannot be stopped by any force on the face of this god given free land.

Mike: "God dammit wei, i thought i told you to control yourself when we are walking on the street. You always go nuts when a black chick walks by, this is the third time you've taken your cock out and asked her to jack you off like a goddamn baboon."

Wei: "Ahh man come on. I just have that Chris Ryan Disease. It's a medical condition and not my fault. When i see a black girl, this sexual urge comes over me and i can not control myself."

by bridget rowland December 17, 2008

Tay-Sachs Disease

Tay-Sachs disease is a rare genetic disorder in which an enzyme called hexosaminidase-A is missing. This enzyme is vital in breaking down harmful substances known as lypids. When these lypids build up in the brain they cause brain dammage, and cause death usually by the age of 3 to 5 years of age. Its autozomal recessive so both the wife, and the husband have to be carriers of the Tay-Sachs ghene to have a possibility of having a child affected with Tay-Sachs disease. If both partners are carriers they have a 1-4% chance of having a child affected with Tay-Sachs disease. Tay-Sachs disease is ALWAYS fatal.

When Fred was born genetic tests showed that he had Tay-Sachs disease disease. He died at the age of 3 years.

by ventilator98 April 4, 2009