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Referring to a perspective or view from the context of a fictional world, in contrast to a perspective from the real world.
Guy 1: What's the in-universe explanation for Pokémon Trainers using Pokémon for Pokémon battling.

Guy 2: Pokémon trust People? That's the in-universe explanation
by UnlimitedMew123 February 9, 2019
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Like a "piss in the ocean", but on a much grander scale.
I own $6,000,000,000 and i just dropped $10,000 down a drain. oh well, that's just a piss in the universe for me
by akkuukniep November 22, 2011
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In an episode of South Park, John Edward the "psychic" (not to be confused with John Edwards the politician) was nominated for the Biggest Douche In The Universe award by Stan.

Near the end of the show a ship full of aliens landed on the set of John's tv show and congratulated him for being nominated before taking him on a trip to another planet for the intergalactic B.D.I.U. awards ceremony. John Edward wound up winning the title of "Biggest Douche In The Universe" despite repeated protests that he wasn't a douche. Edward beat out several other nominees, including an alien who was literally a giant living, breathing douche bag with a nozzle and everything!
by Rabid_Caterpillar September 16, 2004
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Best Page in the Universe is a website created by a writter called Maddox. This site features articles ranting about his hate towards children, old people, women, and the Titanic. He is an amazing writer who will bash the daylights out of anyone or anything he likes. There is a society called Mothers Against Maddox. This group tries to get Maddox of the internet, and want to shut down his site. His articles feature loads of foul language, and adult material.
Best Page in the Universe is THE Best Page in the Universe.
by Maddox4Everyone July 2, 2008
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1. A term used on the television show "South Park" to refer to the psychic John Edward, who claims to channel the dead family members of the peole in his studio audience. In the episode of South Park, John Edwards is given "The Biggest Douche In the Universe" award by members of the intergallactic community.

2. This year, the biggest douche in the Universe award goes to John Mark Karr. This attention seeking pedophile is getting the attention he wants by the second biggest douche in the universe---the American media.
I am tired of seeing The biggest douche in the universe, John Mark Karr on the news every time I turn on MSNBC and CNN.
by Nikki4mets August 24, 2006
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DENZEL WEB DENZEL WEB DENZEL WEB DENZEL WEB LOVE AT PEACE LOVE AT PEACE SUNDOWN SUNDOWN SUNDOWN
Tyler: Yo have you heard Sundown by Denzel Web?
cosmic: Nigga that shit sounds like ass nuggets
Tyler:You tripping nigga,hating ass faggot that shit slaps! Denzel Web the best music artist in the universe right now
by Tyler the realeast nigga April 3, 2019
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