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A contraction of His Honor. Not city-centric, but used regularly in New York City newspapers, usually to set an informal tone about a public official.
"Hizzoner would have none of it."
Hizzoner by Customer1 December 28, 2005
Instead of saying, "these are my bitches"
say "these are my hizzoes."
Hizzoe by Momma Hizzoe February 11, 2010
(1)As a greeting or as a farewell, to be used in general speak as a substitute for a much better, more difficult salutation.
(2) As a substitute for an affirmative response.
(3) As a substitute for virtually any interjection.
(1)Fred: I'll see you tomorrow, Chuck.
Chuck: OK Fred. Hizzoo!

(2)Fred: Are you going to the movies?
Chuck: Hizzoo!

(3) (A) Fred: Jeter just hit a Home
Run. Hizzoo!
(B) Fred: I won! I won! Hizzoo!
(C) Fred: Didn't that movie rock?
Chuck: Hizzoo!
Hizzoo! by Christopher Graham August 26, 2005
dat bi-a-tch is up in my hizous
Shawty in da hizzous

hizzouse 

the place of someones residence, particularly, your own house
Yo, lets take it to the hizzouse!
hizzouse by nick pizzayne December 3, 2002