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Jeffies are opioid analgesic medication synthesized from opium-derived thebaine. In other words any form of opioid medication. Usually in the form of but not limited to; oxycodone or hydrocodone. Many name brands of "Jeffies" are; Oxycontin "The King Jeffi", or weaker forms of "Jeffies" sch as Loraltab or Percocet. Other forms of "Jeffies" are such forms of opioid such as methadone, codeine, morphine, and even on some cases heroin. The name "Jeffi" derives from the people who sell drugs like these. When buying such drugs you have to deal with low life's that aren't legally named "Jeffi" but just look like they should be. This is from things like being overweight and having bent up glasses and being over medicated on Jeffies at all times.
Hey man you wana celebrate and grab a couple jeffies and watch a movie?" or "Dude im so jeffied right now I don't know when I'm asleep or when I'm awake its crazy brah." or "Man I love Jeffies but I hate Jeffi.
Jeffi by Da Beaks January 21, 2011
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Jefferson Wingy

The man, the myth, the Cleveland Metropolitan Area Legend. Major supporter of all things cannabis and proponent and supporter of Chief Wahoo.
Man, Jefferson Wingy knows everything there is to know about smoking trees and Bob Feller.
Jefferson Wingy by FartingBeer April 8, 2021
Related Words

Jeffery Bezos 

Jeffery Bezos, Jeffery Bezos, Jeffery Bezos: You did it!
Jeffery Bezos by gay.sea.otter July 13, 2021

Alshon Jeffery 

That guy: I’m open *ball slips out of hands*
That guy just did an Alshon Jeffery

Boom Tetris for Jeff

A meme about the game Tetris that originates from a quote from the Classic Tetris World Championships of 2016. When a player named Jeff did a Tetris (clearing 4 rows at once), the host said this.
A: *does a Tetris*
B: Boom Tetris for Jeff
A mythical gym creature capable of moving seemingly impossible amounts of weight all while demonstrating below average form. Some say you can identify a Bro Jeff by seeing them front squat 315 lbs with a wide stance and overextending the knees.
"Wow, look at Bro Jeff lifting all that weight.ā€
bro jeff by BroJeffEnthusiast March 27, 2019

Uncle Jeff 

The act of using the internet, especially Facebook to stalk and learn everything about a person.
That girl is really cute I'm going to Uncle Jeff her tonight.
Uncle Jeff by Nexvita August 6, 2011