tissue issue

When you need a tissue, but don't have one on your person, which then causes an issue

I almost had a tissue issue but i had a tissue in my pocket and therefore there was no issue.

tissue issue by gutter-ball j May 18, 2008

Tissue Issue

A human resource issue when someone is whining and a mock tissue to wipe the eye is necessary.

Also a human resource issue involving people rather than equipment or processes.

Are you whining? This sounds like a tissue issue.

We've got another tissue issue, the warehouse crew is bitching again.

Tissue Issue by C. Wright May 10, 2005

One Tissue Issue

Busting a nut and only needing one tissue to clean it up

My nut today to a picture of Timmy’s mom was a one tissue issue.

One Tissue Issue by From the L to the A February 12, 2018

ISSUE TISSUE 

CODE NAME FOR SANITARY NAPKINS

GIRL ONE: HEY JENNY I NEED TO GO HOME FOR A MOMENT. MY PERIOD IS HERE AND I DON'T HAVE ANY TAMPONS HERE.
GIRL TWO: OH DON'T WORRY, I KEEP A SUPPLY OF ISSUE TISSUE WITH ME.

ISSUE TISSUE by Gemini12 May 20, 2015

tissue for your issue 

See cheese with your whine, but has some stronger implications - namely that the recipient of the comment actually did have it coming, and there is no room to complain, with the implication that the recipient should quit bawling about it for that very reason.

Oh, the IRS is collecting from you after you decided to protest your taxes? Well, then, you want some tissue for your issue?

tissue for your issue by ke6isf October 22, 2004

no issue no tissue 

Not sure how this has no definition yet and generally isn't a more common used figure of speech, because it works in multiple ways.
So, basically

1: If you don't spill anything on the floor, you're not going to have to clean it up
"Can I trust you to work alone for a bit?"
"Yeah bruh, no issues, no tissues"
2: If there's no problems, then you don't need anything to wipe the tears out of your face

"I'm fine"
"You been crying, no issues no tissues sis"
3:

A way to respond to someone inquiring requests from you that you currently don't have any
"Dude, should I get you anything from da store?"
"No issues, no tissues homeboy"

4:
When someone expects one of your experiences to have been way more intense than they really were

"Fell down de stairs"
"Ahh shit musta sucked homie"
"Nah brotha, no issues, tissues"

Look above cunt
No issue no tissue
Ya happy urban dic

no issue no tissue by Petra Jansen November 10, 2019

Same Issue, Different Tissue 

The same old shit occurring from the same old shitty people!

That slut bag WHORE banged my skinny, faggot boss. Same issue, Different Tissue!

Same Issue, Different Tissue by Jeffrey Olivo October 1, 2015