Etymology: "man" + "catastrophe"
Meaning: Some sort of disaster involving a man. Usually has something to do with a girl, although major injuries, missing a football game, and midlife crises also count.
I had a total mantasrophe the other day; I missed the big game and my girlfriend broke up with me. I suck. Think I'll go get a beer or something.
The ensuing chaos/disaster of a person who's mental state was either permanently or temporarily destroyed from doing too many math problems in one day.
After doing 150 polynomial and factorization problems, a mathtastrophe occurred destroying millions of dollars of property and a loss of life estimated in the thousands.
fan·tas·tro·phe
A moment or circumstance in fantasy sports that suggests a significant loss that could pertain to a performance, player, owner or match-up.