dryfist Share definition Flag To insert a whole (usally clenched) fist into your partners anus and/or vagina. Without the aid of lubrication. "bobby dryfist(ed) my anus last night and now I'm shitting blood." dryfist by MrMagoo January 14, 2005 0 0 Get merch Get the dryfist mug. Buy Now — $32.95 See more merch