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disastrophe 

A combination of the words 'disaster' and 'catastrophe' indicating a very serious and very tragic event. A tragedy of epic proportions.
The flood was a disastrophe for that region of the United States.
disastrophe by Bob_Lob_law September 10, 2010

disastrophe 

A really, really bad problem. Worse than a disaster, worse than a catastrophe.
Did you see how he screwed up the presentation? It was a disastrophe!
disastrophe by Rick Rodrick September 24, 2003

Disastrophe 

A combination of disaster and catastrophe taking place, usually in the workplace and sometimes involving doughnuts
Guy: I can't believe he ratted us out to the client for blowing off the meeting to go for doughnuts...

Girl: What a disastrophe!!
Disastrophe by AndyHay. March 10, 2010

disastrophe 

A situation or event which scores, in severity, between disaster and catastrophe on the problem scale.
When Maddy realised, after a night of crying about her latest failed relationship, that she had an important Physics test the following day, she declared the situation a disastrophe, and continued sobbing.
disastrophe by gangstayo December 29, 2009

destrastrophe 

A catastrophe that occurs when a celebrity enters the room or a catastrophe on a much larger scale
When she saw him sit at the bar, it set off a destrastrophe that caused her to drop a case of prosecco, which the waiter tripped over, causing him to launch several entrees in to the air, landing all over the bistro.
destrastrophe by Billy Destro April 11, 2011

disastrophe 

a cross between a disaster & a catastrophe. The ultimate wreck!
Don't come in! My place is a total disastrophe! Or that drunk chick is a mess! She's a disastrophe waiting to happen!
disastrophe by chocolate chick76 October 30, 2009