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A thotty bitch that "hops" (like a frog) male to male. She also is really good at "hopping" on dick. (Also a frog reference.) Popular words by Sahbabii in the song Marsupial Superstars.
"Yo, that bitch be an amphibian. "
"I want to Fuck an amphibian"
Amphibian by Tha Punisha June 25, 2017
An amphibian is someone who switches up when you're not around, such as being fake, unloyal, untrustworthy or a snitch, much like then term snake but an amphibian is way worse then just that, to earn an Ampbihian title is a death sentence in the mean streets of NorthEast Philadelphia where the term originates, further more a amphibian can be marked either verbally within a group or by sending and/or commenting different reptile/Ambphian emojis on their social media
Example #1

Bro #1 "yo you see Shaun boo'd up with your ex on the gram ? "

Bro #2 "nah but I'm not surprised that n*gga always doing some amphibious behavior"

Example #2

Bro #1 "bro I was at the mall and mark dabbed up my ex's new boyfriend like he was his man's "

Bro #2 "dawg I seen that n*gga sun bathing yesterday, I knew that he was a Amphibian"

Example #3

"yo bro I see them n*ggas that set you up last week, I'm bouta pull up on them Amphibian as n*ggas"

Example #4

Bro#1 "yo what the f*ck Mrs Smith failed me when she said if I did this project she'd give me a passing grade"

Bro#2 " She did the same thing to me, what a Amphibian b*tch"
Amphibian by JR savage June 13, 2018
A poor poker player - equally bad in tournaments and regular play.
Lawfi5h is an amphibian.
Amphibian by Cohete November 17, 2004
A methamphetamine user,drug addict or junkie who's characteristics are slimy like a lizard or a frog
Damn my car just got jacked by those amphibians
Amphibian by Maddbutch April 8, 2019
A fecal specimen which straddles the porcelain coast, partially in and partially out of the water. An amphibian is neither a floater nor a sinker, until forced back into the icy depths. Usually type 3 or 4 on the Bristol Stool Scale.

Amphibians rarely go undetected because they are very heavy breathers. But if they do go unnoticed and manage to survive the whirlpool they are likely to expire on shore and become a sticktite.
Hey Todd, have you ever noticed the the amphibian assault effect up on 12 every Thursday morning? You think it has anything to do with Bagel Wednesday?
amphibian by dook dook baby September 22, 2008
grosssssss did u see that thing?! wat an amphibian
amphibian by gus July 9, 2003