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Stands for Monthly Vaginal Bleeding. A synonym for a woman's period, or menstruation.
Megan's MVB was finally over after 5 days.
MVB by Borimir August 16, 2009
Related Words
Most Valuable Bitch, the most important female; the 1st lady. Queen B (Lil' Kim) For Bad Boy Records.
Dat chick is the MVB of th clique ya na, so you best show some respect.
mvb by Pecknarm's MVB December 31, 2006
Doing a girl in the mouth, vaginal, and then butt

or

Massive Vaginal Boner aka crazy swollen clit
Yo brah, I fuckin' MVB'd some freshman last night at that party!
Dude, fucked this chick last night with a fucking MVB. It was bigger than Kenny's cock.
MVB by lielia November 21, 2011
Friend 1: "Does MVB really stand for modesto virtual bathroom?"

Friend 2:"Maybe. Maybe not."
MVB by Horchataisntthatcool17 January 13, 2009
Most Vauluable Button
my previous channel button is my MVB
MVB by Stephanie Light April 2, 2008
Them MVB’s ah different vibe😩💞
MVB by Lover_bou April 24, 2020