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LSMISOYNK 

Modern term like LOL or ROFL, meaning:

"laughing so much I stomped on your new kitten".

A popular phrase, which definitely needed shortening to an easy to remember version like LSMISOYNK.
Person 1: I found that bloke in a public toilet, "having fun" with baked beans

Person 2: LSMISOYNK
Related Words
That was so funny ilshismp.
lshismp by Jon February 8, 2004
Danz: OMFG! You just raped my ears! You forcefully shoved info into them which I did not want!
Royal: lshism
lshism by Royal Celebi August 4, 2007

LSHISMGDOMFC 

Laughing so hard I spilled my grape drink on my fried chicken.

Used to imply the stereotype among black people loving grape drinks and fried chicken.
Black Guy 1: Why is 6 afraid of 7?
Black Guy 2: Why?
Black Guy 1: Because 6 is afraid of 7!
Black Guy 2:LSHISMGDOMFC!
Wow, you do a lot of blow!

LSHISMB!
LSHISMB by Marty McFriend June 4, 2005
Kevin: Hey John, the dog just stole my wooden leg.
John: LSHISMP
LSHISMP by LachyGordon May 19, 2005