AFE Share definition Flag AFE: Acronym (Attractive Female Entities). Used to describe female entities which posses a level of attraction that can produce arrousal of the male (and sometimes female) gender. Hey man let's go find us some fuckin AFE's. AFE by adag_dode October 11, 2009 0 0 Get merch Get the AFE mug. Buy Now — $32.95 See more merch