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What it do baby boo? 

Snoop Dogg’s opening line in The Pussycat Dolls’ song “Buttons” featuring snoopy.

It basically means ‘what can that ass do?’, but in an iconic snoop dogg-way
Snoop guy: ‘Damn, what a nice ass you got. What it do baby boo?’
Girl w/ nice ass: ‘A lot. Jump on that di*k for starters.’

What It Do TV 

The Realest Channel on Youtube, Devoted to Keeping it Real 1000% No Refunds
Yo, did you catch that episode of what it do tv? Its realness was off the hook!
What It Do TV by What it do. July 5, 2017

Thas What It Do Frank 

when something gets achieved, finished or completed.
when you feel or like you did something good

or you can just say thas what it do frank because THAS WHAT IT DO FRANK

originator: FRANK LOPEZ VS NOOBS
when thas what it do like thas what it muthafuckin do frank
random nigger: thas what it do maine?

You: thas what it do frank

thats what it do 

When Someone asks what it do, and you do something, you respond with "thats what it do" Or when you make a definate statement.
ex 1) guy 1: "what it do with that new whip?"
guy 2: (does a donut or figure 8) "thats what it do"

ex 2) Killa Keise - "I can go home and pull 50 racks out that Jordan box, thats what it do nigga, they call us guap gang from now on nigga:"
thats what it do by Thizztapher February 28, 2008

Do what it do 

The act of making something do its intended function.
"Aww yeah, I'm gonna make it do what it do!" - Stinkmeaner
Do what it do by Bert Brocone April 23, 2008

It be what it do 

a term used by streamers to say "it is what it is" in a unique way
Streamer: *Reading chat* oh you can't sub next month? Its alright man it be what it do.
It be what it do by dawndeviant August 22, 2020