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"I've had it with these motherfucking snakes on this motherfucking plane!" 

A phrase one hollers when one is sick and tired of a situation. From the film, "Snakes on a Plane"
After hours of dealing with bureaucrats, John suddenly shouted "I've had it with these motherfucking snakes on this motherfucking plane!"

worthless motherfucker 

To be completely without worth, and a motherfucker at the same time.
Those guys sure are a bunch of worthless motherfuckers!

mushroom-cloud-laying motherfucker 

Phrase first used by Samuel L. Jackson in the greatest movie of all time, "Pulp Fiction".

Translates to "uber-badass from hell".
"Well, I'm one mushroom-cloud-laying motherfucker, motherfucker!"

what the motherfuck 

A phrase uttered when no other forms of expression suffice. Used to describe a situation that is larger than one person, completely out of control and beyond explanation.
What the motherfuck. That situation was FUBAR.

motherfucking snakes on a motherfucking plane 

The last thing that you will hear when you are being attacked by numerous snakes on a motherfucking plane. Also used as a term in which you are completely fed up with a problem that you have been dealing with.
Sam Jackson: I have had it with these motherfucking snakes on a motherfucking plane!

Surprise Motherfucker 

When a black dude approaches you unexpectedly
" Surprise Motherfucker" .... "oh shit dude you scared me!"
Surprise Motherfucker by Zoku February 12, 2013